Modified Penicillin Molecule with Carbapenem-Like Stereochemistry Specifically Inhibits Class C β-Lactamases | Antimicrobial Agents and Chemotherapy
The hydrolytic water molecule of Class A β-lactamase relies on the acyl-enzyme intermediate ES* for proper coordination and catalysis | Scientific Reports
Beta-lactam - Wikipedia
Beta-lactam Antibiotics and Cross-reactivity
β-Lactam synthetase: A new biosynthetic enzyme | PNAS
β-Lactam antibiotic targets and resistance mechanisms: from covalent inhibitors to substrates - RSC Medicinal Chemistry (RSC Publishing) DOI:10.1039/D1MD00200G
Osmosis from Elsevier - Penicillins are antibiotics that belong to the group of beta lactams, which have a beta-lactam ring in their structure that helps inhibit cell wall synthesis in bacteria. As
Yexel Exams - Beta-lactam antibiotics are among the most commonly prescribed drugs, grouped together based upon a shared structural feature, the beta-lactam ring. Beta-lactam antibiotics include: ○Penicillins ○Cephalosporins ○Carbapenems ...
Frontiers | Structural and Mechanistic Basis for Extended-Spectrum Drug-Resistance Mutations in Altering the Specificity of TEM, CTX-M, and KPC β-lactamases